Drug Category
|
Brand and Generic Name
|
How it works
|
Advantages
|
Disadvantages
|
Alpha-glucosidase Inhibitors
|
Glyset, Precose
|
Blocks the absorption of some carbohydrates in the
intestine
|
Lowers blood glucose after meals, does not cause
low blood glucose
|
May cause gas, bloating and diarrhea.
|
Biguanides
|
Glucophage
|
Helps the body use it's own insulin better:
muscles use more glucose and the liver makes less glucose.
|
Does not cause low blood glucose, may help with
weight loss and can improve blood lipids (fats).
|
Can't take if you drink alcohol excessively. Can
cause nausea and diarrhea when started.
|
Meglitinides
|
Prandin |
Reduces blood glucose levels by stimulating
insulin release form the pancreas. |
Rapidly absorbed by the body. Can be used alone or
with metformin.
|
Can cause blood glucose to get too low.
|
Thiazolidinediones
|
Actos, Avandia
|
Works to decrease insulin resistance and improves
the muscle's ability to use insulin. Does not make more insulin. > |
Cannot cause blood glucose to get too low if it is
the only diabetes pill taken. |
Can cause liver problems. Some birth control pills
may not work. |
Sulfonylureas |
Diabeta, Glucotrol XL
Amaryl, Micronase, Glynase
Generic: Glyburide, Glipizide
|
Lowers blood glucose by helping the pancreas
produce more insulin.
|
These are 2nd generation drugs with fewer side
effects than older sulfonylureas.
|
Can cause blood glucose to get too low.
|