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 Sleep  Holistic-online.com

Methylphenidate

Brand Names

bulletPMS Methylphenidate
bulletRitalin SR
bulletRitalin

Drug class: Central nervous system stimulant, sympathomimetic

Uses

bulletDecreases overactivity and lengthens attention span in children with attention-deficit hyperactivity disorder (ADHD). It is used as part of the total management plan that includes educational, social and psychological treatment.
bulletTreatment of depression in adults.
bulletTreatment for narcolepsy and other disorders.

What drug does

Stimulates brain to improve alertness, concentration and attention span. Calms the hyperactive child. It is a dopamine agonist.

Dosage

For Narcolepsy:
Common initial dose - 5 mg once or twice daily 
Usual maximal dose (carefully monitored higher doses may sometimes be required) - 30 mg am and noon (short-acting, sustained-release or combination)

Overdose

Symptoms: Rapid heartbeat, fever, confusion, vomiting, agitation, hallucinations, convulsions, coma.

What To Do in case of overdose: (Life Threatening)

bulletDial 911 (emergency) or call an ambulance or call for medical help.  Then give first aid immediately. Or go to emergency room immediately.
bulletIf patient is unconscious and not breathing, give mouth-to-mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). Don't try to make patient vomit. If you can't get help quickly, take patient to nearest emergency facility.


 Side Effects

Possible Adverse Reactions Or Side Effects
Symptoms What To Do
Life-threatening:

Rapid heartbeat, fever, confusion, vomiting, agitation, hallucinations, convulsions, coma.

These are signs of drug overdose. Get medical help immediately. See above.
Common:

Nervousness, trouble sleeping, dizziness, nausea, appetite loss, headache, drowsiness, stomach pain, weight loss. 

Continue taking medication. Call doctor when convenient. 
Infrequent:

Rash or hives; chest pain; fast, irregular heartbeat; unusual bruising; joint pain; psychosis; uncontrollable movements; unexplained fever. 

Discontinue taking medication. Call doctor right away.
Rare:

Blurred vision, other vision change, sore throat, unusual tiredness, convulsions.

Discontinue taking medication. Call doctor right away.

Adverse reactions and side effects may be more frequent and severe for those over 60 than in younger persons.

Warnings & Precautions

Don't take medication if:

bulletYou are allergic to methylphenidate.
bulletYou have glaucoma.

Before you start medication, consult your doctor if any of the following applies:

bulletYou have epilepsy.
bulletYou have high blood pressure.
bulletYou take MAO inhibitors.
bulletYou have emotional or psychotic problems.
bulletYou have a history of drug abuse. 

Prolonged use:

bulletRare possibility of physical growth retardation in children.
bulletTalk to your doctor about the need for follow- up medical examinations or laboratory studies to check blood pressure, complete blood counts (white blood cell count, platelet count, red blood cell count, hemoglobin, hematocrit), growth charts. 

Miscellaneous:

bulletDose must be carefully adjusted by doctor.
bulletAdvise any doctor or dentist whom you consult about the use of this medicine.
bulletUse only under medical supervision for children 6 or older. Don't give to child younger than 6.
bulletDon't discontinue abruptly. Don't discontinue without doctor's advice until you complete prescribed dose, even though symptoms diminish or disappear. Report to your doctor any new symptoms of depression, unusual behavior, unusual weakness or tiredness.

Interactions

Possible Interaction With Other Drugs
Generic Name Or Drug Class  Combined Effect 
Anticholinergics Increased anticholinergic effect.
Anticoagulants, oral Increased anticoagulant effect. 
Anticonvulsants Increased anticonvulsant effect. 
Antidepressants, tricyclic Increased antidepressant effect. Decreased methylphenidate effect.
Antihypertensives Decreased antihypertensive effect.
Central nervous system (CNS) stimulants Overstimulation.
Cisapride Decreased methylphenidate effect. 
Dextrothyroxine Increased methylphenidate effect. 
Guanadrel Decreased guanadrel effect.
Guanethidine Decreased guanethidine effect.
Minoxidil Decreased minoxidil effect.
Monoamine oxidase (MAO) inhibitors Dangerous rise in blood pressure.
Nitrates Possible decreased effects of both drugs. 
Pimozide May mask the cause of tics. 
Possible Interaction With Other Substances 
Interacts With Combined Effect
Beverages: 
Caffeine drinks.
May raise blood pressure. 
Cocaine High risk of heart- beat irregularities and high blood pressure. 
Foods: 
Foods containing tyramine.
May raise blood pressure.

 

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