The Story of Free Radicals
Free radicals are the highly unstable
chemicals that attack, infiltrate, and injure vital cell structures. Most stable chemical
compounds in the body possess a pair of electrons. Sometimes, one member of the electron
pair gets stripped away. The resulting compound (that is short of one electron) is called a free
radical.
In chemistry, the term free radical means
that it is now free to combine with another element to form a new stable compound. One way
to think of free radical is the way our social system work. In a family there is husband
and wife. They are joined together. Both are "tied up" or not available for
other partners. Let us assume that they get 'separated'. Now we have two
"free" persons who are looking for other partners to partner with. The way free radicals work, one of these free spouse go
and break up a stable marriage of another couple, by joining with one of the spouses. This
results in the ouster of a person from that family creating a brand new "free
radical" who goes around prowling to find another "compound" to attack. You
can see that free radicals can do lot of harm by forming a chain reaction.
A similar thing happens with free radicals
in the body. When a free radical is born, it goes around the body looking for another
compound to steal an electron from. This breaks up the "contented" couple, that
results in releasing another free radical, and so on. While on the prowl, these free
radicals (which are really the oxidation products from the body) can do tremendous damage
to the delicate machinery of your cells. The most studied free radical chain reaction in
living things is lipid peroxidation. (The term lipid refers to any fat-soluble substance,
animal or vegetable. Peroxidation means the formation of a peroxide molecule. These are
the molecules with the greatest proportion of oxygen molecules. For example,
a water
molecule has two hydrogen atoms and one oxygen atom. Hydrogen peroxide has two Hydrogen
atoms and two oxygen atoms. In other words, there is an excess oxygen atom in
a hydrogen peroxide molecule.)
Ninety eight percent of the oxygen we
breathe is used by tiny powerhouses within our cells called mitochondria, that convert
sugar, fats and inorganic phosphate by combining with oxygen into adenosine triphosphate (ATP), the
universal form of energy we need to live. This energy producing activity of the
mitochondria involves a series of intricate, complex and vital biochemical processes
that depends on vast numbers of enzymes (estimates vary from 500 to 10,000 sets of oxidative
enzymes). These, in turn, depends on dozens of nutrient factors and co-factors. In
this metabolism process, a very small amount of left over oxygen loses electrons, creating
free radicals. These free radicals burn holes in our cellular membranes. Calcium penetrate
our cells through these holes. This excess calcium results in cell death. This, in turn,
weakens tissues and organs. As this damage continues, our body become "rusty",
less able to fight other invaders such as cancer, hardening of the arteries, premature
aging, and other bodily disorders.
Because of the amount of oxygen we breathe
every day (our bodies take 630 quadrillion damaging oxygen hits per day, each
of our cells takes about 10,000 hits per day and each DNA strand in the cell gets hit
5,000 times per day. This free radical bombardment causes a typical human cell to undergo
thousands of changes or mutations daily. If a DNA strand gets hit and is not repaired
before its twin gets hit, we will have the onset of a potentially lethal cancer.
In addition to the oxygen we breathe, the
free radicals can also come from such things as environmental pollution, radiation,
cigarette smoke, chemicals, and herbicides.
The key to having a healthy body is to
repair the damages caused by the free radicals before it is too late, and to protect the
body's tissue cells from the free radicals before they cause mutations. Antioxidants are
substances that have free-radical chain-reaction-breaking properties. Like a bouncer, the
antioxidants deactivate potentially dangerous free radicals before they can damage a cells'
machinery. Most of these antioxidants come from plants and are called phytochemicals. More
than 60,000 of such plant chemicals are identified. Among the most effective and dedicated
antioxidants are Vitamin A, C, and E (known as the ACE trio.). Out of
these, Vitamin C is the most powerful.
Each cell produces its own antioxidants.
But the ability to produce them decreases as we age. That is why our diet
should supply anti-oxidants, phytochemicals ( fruits and vegetables are a
good source for this.) and additional vitamins and
minerals.